Description
Tamoxifen 10 mg
Brand: Magnus Pharmaceuticals
Content: 100 tablets | 10 mg per tablet
Price: €29
Manufactured in: Europe
🧪 Product Overview
Tamoxifen 10 mg delivers a high-purity selective estrogen receptor modulator (SERM) used extensively in both endocrine and androgen-focused research. By binding to ER-α/β receptors and blocking estrogen-mediated feedback on the hypothalamic–pituitary–gonadal (HPG) axis, tamoxifen promotes a cascade increase in LH, FSH, and endogenous testosterone in male models.
In female models, it remains the gold-standard anti-estrogen for ER-positive tumor protocols. Its high oral bioavailability (~100%) and long half-life (4–11 days for parent, up to 70 hours for active metabolite endoxifen) support once-daily use in long-range studies, including PCT, fertility, gynecomastia reversal, and hormone-modulation assays.
✅ Key Research Highlights
HPG-axis stimulation:
10–20 mg/day for 3 months doubled serum testosterone in hypogonadal males [PMC]
Gynecomastia control:
Clinical data show significant breast tissue regression in AAS-using males on 10–20 mg/day
Anti-estrogen benchmark:
First-line SERM for ER+ breast cancer research and comparative estrogen-blocking trials [NCBI]
Pharmacokinetics:
~100% oral bioavailability; 4–11 day half-life (parent), 50–70 hours (endoxifen metabolite) [Wikipedia]
Storage & stability:
Film-coated tablets stable ≤25 °C with 36-month shelf-life — ideal for long-term protocols [PubChem, PubMed]
🧬 Suggested Laboratory Applications
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HPG-axis and testosterone recovery models
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Gynecomastia reversal and estrogenic side-effect prevention
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SERM benchmarking in ER-positive breast-cancer assays
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Post-cycle therapy research for anabolic models
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Hormone-modulation pharmacokinetics
📊 Technical Specifications
| Field | Data |
|---|---|
| Chemical Name | Tamoxifen (base); supplied as Tamoxifen Citrate |
| Chemical Formula | C<sub>26</sub>H<sub>29</sub>NO (base) |
| Synonyms | Nolvadex; TMX; 4-(1-dimethylaminoethoxy)-diphenyl-1-ethenyl-phenol |
| Molecular Weight | 371.5 g/mol (base); 563.6 g/mol (citrate) |
| CAS Number | 10540-29-1 (base); 54965-24-1 (citrate) |
| Half-life | Parent: 4–11 days · Endoxifen: 50–70 hours |
| Detection Window | Long-acting — detectable for several weeks |
| Documented Benefits | ↑ LH/FSH, ↑ testosterone, ↓ gynecomastia, SERM gold standard |
| Main Risks | Hot-flushes, ↓ bone density, cataract risk, thrombo-embolism, lipid shifts |
| Total Active Compound | 1,000 mg tamoxifen base per carton (10 mg × 100 tablets) |
| Shelf-life | 36 months (manufacturer specification) |
❄️ PubChem-Supported Research Insights
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Blocks estrogen feedback to HPG axis → ↑ endogenous testosterone
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Used clinically in both male infertility and female ER+ oncology
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Demonstrated ability to reverse steroid-induced gynecomastia
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Maintains receptor suppression up to 6 weeks post-use
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Oral form preferred over injectable SERMs for logistical ease
⚠️ Documented Research Side Effects
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Hot-flushes, fatigue, and temporary visual disturbances
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Lipid profile changes (↑ LDL / ↓ HDL) with long-term use
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Thrombo-embolic events in susceptible models
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Cataract formation risk at extended exposure
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Reduced bone-mineral density (BMD) with prolonged protocols
🧯 Handling & Compliance
For Research Use Only — Not for human or veterinary use
Store at 15–25°C, protect from light and moisture
Purchase confirms qualified researcher status
Listed on WADA Prohibited List S4 (Hormone Modulators) — any exposure may trigger positive test
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