Methandienone (Dianabol) 10 mg
10 mg · 100 tablets · Methandienone (Dianabol) is a reference-standard oral AAS used in research on androgen-receptor activation, anabolic signaling, nitrogen retention, steroid metabolism, and estrogenic conversion pathways.
€ 39.00
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Methandienone (Dianabol) 10 mg — La Pharma
Brand: La Pharma
Category: Oral AAS Research Compound
Content: 100 tablets × 10 mg (1,000 mg total)
Price: €39
Manufactured in: Thailand
🧪 Product Overview
Methandienone (methandrostenolone) 10 mg is a classic 17-α-alkylated anabolic-androgenic steroid (AAS)
developed for oral activity and widely used in laboratory settings for androgen-receptor (AR) signaling research,
protein synthesis studies, nitrogen-balance modeling, and steroid metabolism analysis. Its ability to aromatize to
17-α-methylestradiol provides a unique intersection of androgenic and estrogenic pathways, making it
scientifically valuable in multi-hormonal anabolic research.
Dianabol originated from mid-20th-century pharmaceutical development and has since become one of the most extensively
studied oral anabolic agents. Its well-documented pharmacology and metabolic behavior make it ideal for both analytical
method development and comparative AAS research.
✅ Key Research Highlights
Potent AR agonist:
Methandienone binds to the androgen receptor, up-regulating anabolic gene transcription, protein synthesis, and nitrogen retention.
Aromatization to methylestradiol:
Its estrogenic conversion (unique among some oral AAS) allows study of water balance, estrogenic activity, and
endocrine cross-interactions.
Oral bioavailability:
17-α-methylation slows hepatic deactivation, enabling stable oral dosing in in-vitro and method-development research.
Historical data-rich compound:
Robust literature exists on lean-mass changes, metabolic alterations, hepatotoxic endpoints, and endocrine disruption.
🧬 Suggested Laboratory Applications
- Androgen receptor signaling and anabolic transcription studies
- Protein synthesis & nitrogen retention assays
- Comparative metabolism of aromatizable vs. non-aromatizable steroids
- Hepatotoxicity and metabolism studies on 17-α-alkylated steroids
- Estrogenic pathway modeling via aromatization products
📊 Technical Specifications
| Field | Value |
|---|---|
| Chemical Name | Methandienone (INN) / Methandrostenolone |
| Chemical Formula | C20H28O2 |
| Synonyms | Methandrostenolone; Metandienone; Dianabol; DBol; 17α-Methyl-Δ¹,⁴-testosterone |
| Molecular Weight | 300.44 g/mol |
| CAS Number | 72-63-9 |
| Compound Class | 17-α-alkylated anabolic-androgenic steroid (AAS); AR agonist |
| Research Notes |
Orally active AAS; increases lean mass & strength in controlled studies; carries hepatotoxic risk; aromatizable to methylestradiol; WADA S1 prohibited. |
| Dosage Form & Pack | Oral tablets, 10 mg × 100 tablets (1,000 mg total) |
| Shelf Life | 36 months (store cool, dry, and protected from light) |
| Country of Manufacture | Thailand (La Pharma) |
❄️ PubChem-Supported Research Insights
- Strong AR-binding and transcriptional upregulation
- Aromatization yields estrogenic metabolites relevant in water balance and gynecomastia models
- 17-α-alkylation increases hepatotoxicity in metabolic studies
- Supports comparative studies on oral steroid metabolism
- Widely used in anti-doping detection research due to characteristic metabolites
⚠️ Documented Research Side Effects
- Hepatotoxicity, including cholestasis and transaminase elevation
- Dyslipidemia (↓ HDL / ↑ LDL) and hypertension markers
- Endocrine suppression and HPTA downregulation
- Estrogenic effects via aromatization (fluid retention, gynecomastia)
- Androgenic effects: acne, alopecia, sebaceous activity changes
- Reported behavioral effects in some models (aggression, mood shifts)
🧯 Handling & Compliance
For Research Use Only — analytical/in-vitro reference compound; not intended for human or veterinary use.
Methandienone is prohibited under WADA S1 and regulated as an AAS in many jurisdictions.
Appropriate chemical-safety procedures, secure storage, and regulatory compliance are required.
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