Salbutamol 4 mg Tablets
4 mg · 100 tablets · Salbutamol is a short-acting, selective β2-adrenergic receptor agonist widely used as a benchmark bronchodilator and β2-selectivity probe in respiratory pharmacology, cAMP signaling research, and anti-doping compliance studies.
€ 39.00
Beskrivelse
Salbutamol 4 mg Tablets — Swiss Remedies
Brand: Swiss Remedies
Category: β2-Adrenergic Research Compound
Content: 100 tablets × 4 mg (400 mg total)
Price: €39
Manufactured in: Switzerland
🧪 Product Overview
Salbutamol (USAN: albuterol) is a short-acting, selective β2-adrenergic receptor agonist used
in laboratories as a reference bronchodilator and β2-selectivity probe. It relaxes airway
smooth muscle via β2-receptor activation, cAMP elevation, and PKA-mediated reduction of intracellular calcium.
Because of its well-defined pharmacology, salbutamol is a core comparator in respiratory and receptor-target
studies.
✅ Key Research Highlights
β2-agonist benchmark:
Canonical reference for bronchodilation, cAMP signaling, β2-selectivity, and smooth-muscle physiology studies.
Exercise physiology & anti-doping relevance:
Controlled studies show no performance improvement in non-asthmatic athletes at inhaled doses up to
1600 μg/24 h (JSSM). Used extensively in anti-doping pharmacokinetics research.
WADA compliance modeling:
WADA permits only inhaled salbutamol ≤1600 μg/24 h; oral/systemic administration is prohibited.
Urinary threshold: ~1000 ng/mL (S3 Beta-2 Agonists).
🧬 Suggested Laboratory Applications
- β2-receptor pharmacology assays
- Bronchodilator response and smooth-muscle relaxation studies
- cAMP/PKA signaling models
- Receptor selectivity and structure-activity analyses
- Anti-doping threshold and detection research
📊 Technical Specifications
| Field | Data |
|---|---|
| Chemical Name | Salbutamol (Albuterol) |
| Chemical Formula (base) | C13H21NO3 |
| Molecular Weight (base) | 239.31 g/mol |
| CAS Numbers | Base: 18559-94-9; Sulfate: 51022-70-9 |
| Class / Target | Short-acting β2-adrenergic receptor agonist (β2AR) |
| Strength / Pack | 4 mg per tablet × 100 tablets (400 mg total) |
| Storage | Store dry, cool, and protected from light; follow SDS |
| Shelf-Life | 36 months (per COA/label) |
❄️ Mechanism of Action (Laboratory Context)
Activation of β2-receptors (Gs-coupled) → stimulation of adenylyl cyclase →
↑ cAMP → PKA activation → reduced intracellular Ca2+ & MLCK activity → smooth-muscle relaxation
and bronchodilation.
⚠️ Documented Research Side Effects
- Tremor and fine-muscle activation
- Tachycardia and palpitations (β1 spillover at higher doses)
- Hypokalemia via β2-mediated potassium shift
- Lactic acidosis in high systemic exposures
- Hyperglycemia and metabolic shifts
- Rare hypersensitivity reactions reported in clinical labeling
🧯 Handling & Compliance
For Research Use Only — not a medicine, supplement, or veterinary product.
Buyer affirms qualified laboratory use and compliance with institutional SOPs and local regulations.
Salbutamol is regulated under WADA S3 Beta-2 Agonists; systemic/oral use is prohibited without a TUE.
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